Triple Combination Cream

18+ · Prescription-only — consult your prescriber. We hold no product. Disclaimer.

Hydroquinone + retinoid + corticosteroid in one cream — the standard of care for melasma. Each active covers a weakness of the others, which is why the combination beats single-ingredient hydroquinone in trials.

Sold in the US as Tri-Luma. It is the one compound in our Pharmacy vertical a discount coupon barely touches.

What it actually costs

10.7× cheaper overseas — and a coupon barely dents it

Route Price Per gram
US retailTri-Luma 30g $299.98 $10.00
US, free GoodRx couponno account, no membership $233.42 $7.78
US, GoodRx Companionnot offered — brand-name drug
Overseas, GMP-verifiedAjanta Pharma · 15g $10.92 $0.728

Checked 15 Aug 2026 · ZIP 37996 · varies by pharmacy — check yours

Why this gap holds. Tri-Luma is brand-only in the US — there is no generic for a coupon to work against. Every other compound here has one, which is why their gaps collapse and this one doesn't.

We could headline 27× by quoting retail. We don't, because GoodRx is free and takes thirty seconds.

Verified sources

  • 🔒 ████████ — ✅ Ajanta Pharma · lowest verified $/g
  • 🔒 ████████ — ✅ Dr. Reddy's · closest to Tri-Luma
  • 🔒 ████████ — ✅ the identical Galderma brand, ~⅓ US price

🔓 Unlock verified sources →

Melasma relapses — these creams manage it, they don't cure it. Sun protection matters more than any cream. How we verify →