18+ · Prescription-only — consult your prescriber. We hold no product. Disclaimer.
The reference skin-lightening agent, prescribed for melasma and post-inflammatory hyperpigmentation. It inhibits tyrosinase, the rate-limiting enzyme in melanin production.
What it actually costs · 4%
5.9× — but the combination cream is usually the better buy
| Route | Price | Per gram |
|---|---|---|
| US retail28.35g tube | $85.05 | $3.000 |
| US, free GoodRx couponno account, no membership | $31.66 | $1.117 |
| US, GoodRx Companionpaid, $9.99–$14.99/mo | $25.96 | $0.916 |
| Overseas, GMP-verified30g · 6-tube tier | $5.70 | $0.190 |
Checked 15 Aug 2026 · ZIP 37996 · varies by pharmacy — check yours
Read this before buying. Most melasma protocols use hydroquinone inside a triple combination, not alone — the retinoid and corticosteroid each cover a weakness it has on its own. If that is what you are treating, the Triple Combination Cream is the better page, and the stronger case at 10.7×.
This listing is for people who specifically need hydroquinone alone, or who are cycling off a combination cream.
Verified sources
- 🔒 ████████ — ⚠️ Partial · 4% · 30g · both pharmacies
Why Partial: most sources attribute this brand to Abbott India, one attributes it to Mepromax. We have not resolved that conflict, so we flag it rather than guess.
🔓 Unlock verified sources — $9 →
Hydroquinone is used in cycles, not continuously — prolonged uninterrupted use is associated with ochronosis. Follow your prescriber's schedule.